A procedure that restores the shock-absorbing and lubricating properties of the synovial fluid in people with osteoarthritis of the knee.

The property of a fluid or semi-fluid that causes it to be thick, and resist flowing.

The hyaluronan-containing fluid found in a joint that lubricates and cushions the joint.

An undesirable event occurring during or following the use of a medicine or a medical device.

The area of medicine that is concerned with the causes, development, diagnosis and treatment of diseases of the joints, muscles, and connective tissues.

A joint disease that is characterized by a breakdown of the cartilage and a deterioration of the fluid in a joint; symptoms of osteoarthritis include pain and stiffness.

The branch of medicine concerned with the nature and correction of disorders of the bones, joints, ligaments, or muscles.

Within the joint.

Hyaluronic acid is a natural sugar that is one of the body’s important building blocks filling many different functions and is also found in all the organs in the body.

The ability of a substance, in this case cartilage, to return quickly to its original shape and size after being bent, stretched, or squashed.

The ability to produce the necessary or desired results.

A tough, fibrous protein forming an important part of skin, tendons, bones, cartilage and other connective tissues. Collagen helps hold together the cells and tissues of the body.

Investigations in humans (in this case), to find out the efficacy or safety of medical drugs or devices.

Fibrous, connective tissue found in humans that provides support to skeletal bones at specific sites and forms the smooth surface of joints.

Inspection of the inside of a joint of the body using an endoscope.

A joint disease that can cause joint pain, swelling and stiffness, and/or redness of the skin over the joint.

An undesirable event occurring during or following the use of a medicine or a medical device.