When you have osteoarthritis (OA), the hyaluronic acid (HA) in the synovial fluid of the affected joint becomes diluted and breaks down faster – reducing its natural protective properties.3 This is associated with increased inflammatory activity in the affected joint that can degrade cartilage tissue.3
This joint inflammation causes local pain receptors to become activated during normal physical movement.3 The pain tends to cause OA patients to limit their joint movements. Because physical movement is required for healthy joint structures and normal synovial fluid activity, limited movement of a joint contributes to further deterioration of structures in the joint and the protective quality of synovial fluid. This process can become a vicious cycle as OA becomes progressively worse and quality of life is severely diminished for OA sufferers.
DUROLANE is a single-injection treatment to relieve the pain of OA in specific small and large joints by supplementing the less healthy HA in an affected joint.7 Hyaluronic acid is a naturally occurring molecule that provides lubrication and cushioning in a normal, healthy joint. The HA in DUROLANE is produced by a safe and proven technology of stabilization called NASHA®.