Factors Related with the Time to Surgery in Waiting-list Patients for Knee Prostheses
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Jurado MR, Fidalgo AE, Villar VR, Medina JM, Lopez BS.
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Jurado MR., Fidalgo AE., Villar VR., Medina JM., Lopez BS. Factors Related with the Time to Surgery in Waiting-list Patients for Knee Prostheses. Reumatol Clin. 2013;
Level-II clinical study: single centre, retrospective cohort study.
To assess if DUROLANE treatment could delay the need for a total knee replacement.
Data was collected on 224 patients requiring TKR, 202 (90.2%) of these patients were treated with DUROLANE. KL grades varied from grade I to grade IV (9% KLI, 27.5% KL-II, 48.2% KL-III, 15.3% KL-IV). In the stratified analysis, treatment with DUROLANE extended time until surgery in the group of patients with KL-III close to statistical significance (P=0.064). The median survival of patients with grade 3 lesions and DUROLANE treatment was 1278 days (95%, 474–2081) and for those not receiving treatment it was 596 days (95% CI, 14–1179).