Safety, efficacy and predictive factors of efficacy of a single intra-articular injection of non-animal-stabilized-hyaluronic-acid in the hip joint: results of a standardized follow-up of patients treated for hip osteoarthritis in daily practice
Full list of Authors
Conrozier T, Couris CM, Mathieu P, Vincent FM, Piperno M, Coury F, Belin V, Tebib J, Vignon E.
Full AMA reference
Conrozier T., Couris CM., Mathieu P. et al. Safety, efficacy and predictive factors of efficacy of a single intra-articular injection of non-animal-stabilized-hyaluronic-acid in the hip joint: results of a standardized follow-up of patients treated for hip osteoarthritis in daily practice. Arch Orthop Trauma Surg. 2009; 129: 843–848.
Study Design
Level-III clinical study: single centre, uncontrolled study.
Objective
To report on the efficacy and tolerability of a single intra-articular injection of NASHA in patients treated for symptomatic hip OA.
Conclusion
34 patients with primary hip OA ranging from KL grades I – IV were treated with DUROLANE. All clinical variables (Walking Pain, Patient Global Assessment, WOMAC, Lequesne index) decreased significantly between baseline and last evaluation at 180 days. The percentage of “responder” patients according to the OMERACT-OARSI criteria (71% of the assessable patients, 55% of the total number of treated patients) suggested that a majority of patients derived benefit of the treatment.
